A STRATEGY FOR UREA LINKED DIAMINE LIBRARIES

被引:54
作者
HUTCHINS, SM
CHAPMAN, KT
机构
[1] Automated Synthesis Group Department of Molecular Design, Diversity Merck Research Laboratories Rahway
关键词
D O I
10.1016/0040-4039(95)00345-D
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A strategy for urea linked diamine libraries has been developed. The route involves the use of unprotected diamines and a p-nitrophenylcarbamate intermediate for the generation of the urea. The products obtained after 8 steps are of high chemical purity.
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页码:2583 / 2586
页数:4
相关论文
共 2 条
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  • [2] Hutchins, Chapman, Tetrahedron Lett., 35, 24, pp. 4055-4058, (1994)