SOLVENT EFFECTS IN LIPASE-CATALYZED TRANSESTERIFICATION REACTIONS

被引：35

作者：

KANERVA, LT

VIHANTO, J

HALME, MH

LOPONEN, JM

EURANTO, EK

机构：

[1] Department of Chemistry, University of Turku

来源：

ACTA CHEMICA SCANDINAVICA | 1990年 / 44卷 / 10期

关键词：

D O I：

10.3891/acta.chem.scand.44-1032

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Porcine pancreatic lipase-catalysed transesterifications of 2,2,2-trifluoroethyl butyrate with racemic 2-octanol and 1-phenylethanol have been studied in different organic solvents. Solvent hydrophobicity (log P -1.1 to 3.3) has only a minor effect on the reaction rate. Independently of the solvent used as the reaction medium, both (R)-2-octyl and (R)-1-phenylethyl butyrates were obtained in high optical purity (ee greater than 90%). Candida cylindracea lipase is active only in the most hydrophobic solvents studied.

引用

页码：1032 / 1035

页数：4

共 11 条

[1] SCREENING OF LIPASES FOR THE ENANTIOMER RESOLUTION OF R,S-2-OCTANOL BY ESTERIFICATION IN ORGANIC MEDIUM [J].