SIMULATION OF BIOLOGICAL CELL SORTING USING A 2-DIMENSIONAL EXTENDED POTTS-MODEL

被引：915

作者：

GRANER, F ^{[1
]}

GLAZIER, JA ^{[1
]}

机构：

[1] UNIV NOTRE DAME,DEPT PHYS,NOTRE DAME,IN 46556

来源：

PHYSICAL REVIEW LETTERS | 1992年 / 69卷 / 13期

关键词：

D O I：

10.1103/PhysRevLett.69.2013

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We simulate the sorting of a mixture of two types of biological cells using a modified version of the large-Q Potts model with differential adhesivity. We find long-distance cell movement leading to sorting with a logarithmic increase in the length scale of homogeneous clusters. Sorted clusters then round. We find two successive phases: a rapid boundary-driven creation of a low-cohesivity cell monolayer around the aggregate, and a slower boundary-independent internal rearrangement.

引用

页码：2013 / 2016

页数：4

共 21 条

[1] COMPUTER-SIMULATION OF GRAIN-GROWTH .1. KINETICS [J].

ANDERSON, MP ;

SROLOVITZ, DJ ;

GREST, GS ;

SAHNI, PS .

ACTA METALLURGICA, 1984, 32 (05) :783-791

[2] CELL SORTING OUT - THE SELF-ASSEMBLY OF TISSUES INVITRO [J].

ARMSTRONG, PB .

CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1989, 24 (02) :119-149

[3] TISSUE-SPECIFIC SORTING-OUT IN 2 DIMENSIONS IN RELATION TO CONTACT INHIBITION OF CELL MOVEMENT [J].

GARROD, DR ;

STEINBERG, MS .

NATURE, 1973, 244 (5418) :568-569

[4] REGENERATION OF HYDRA FROM REAGGREGATED CELLS [J].

GIERER, A ;

BODE, H ;

BERKING, S ;

SCHALLER, H ;

TRENKNER, E ;

HANSMANN, G ;

DAVID, CN ;

FLICK, K .

NATURE-NEW BIOLOGY, 1972, 239 (91) :98-&

[5] DYNAMICS OF TWO-DIMENSIONAL SOAP FROTHS [J].

GLAZIER, JA ;

GROSS, SP ;

STAVANS, J .

PHYSICAL REVIEW A, 1987, 36 (01) :306-312

[6] COARSENING IN THE 2-DIMENSIONAL SOAP FROTH AND THE LARGE-Q POTTS-MODEL - A DETAILED COMPARISON [J].

GLAZIER, JA ;

ANDERSON, MP ;

GREST, GS .

PHILOSOPHICAL MAGAZINE B-PHYSICS OF CONDENSED MATTER STATISTICAL MECHANICS ELECTRONIC OPTICAL AND MAGNETIC PROPERTIES, 1990, 62 (06) :615-645

[7]

Glazier JA, 1989, THESIS U CHICAGO

[8]

GLAZIER JB, IN PRESS

[9] KINETICS OF DOMAIN GROWTH - UNIVERSALITY OF KINETIC EXPONENTS [J].

GREST, GS ;

SROLOVITZ, DJ ;

ANDERSON, MP .

PHYSICAL REVIEW LETTERS, 1984, 52 (15) :1321-1329

[10] EFFECTS OF LATTICE ANISOTROPY AND TEMPERATURE ON DOMAIN GROWTH IN THE 2-DIMENSIONAL POTTS-MODEL [J].

HOLM, EA ;

GLAZIER, JA ;

SROLOVITZ, DJ ;

GREST, GS .

PHYSICAL REVIEW A, 1991, 43 (06) :2662-2668

← 1 2 3 →