THE 7-MEMBERED RING INTERMEDIATE TO CONTROL THE STEREOCHEMISTRY ON THE 8-MEMBERED TAXANE B-RING CYCLIZATION

被引：19

作者：

MORIHIRA, K ^{[1
]}

SETO, M ^{[1
]}

FURUKAWA, T ^{[1
]}

HORIGUCHI, Y ^{[1
]}

KUWAJIMA, I ^{[1
]}

机构：

[1] TOKYO INST TECHNOL,DEPT CHEM,TOKYO 152,JAPAN

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 02期

关键词：

D O I：

10.1016/S0040-4039(00)60584-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

On 8-membered ring cyclization of taxane B ring, formation of 7-membered cyclized intermediate has been identified, and the unique cyclization as well as the isomerization mechanism involving several equilibration processes have been proposed.

引用

页码：345 / 348

页数：4

共 4 条

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[2] A HIGHLY EFFICIENT 8-MEMBERED-RING CYCLIZATION FOR CONSTRUCTION OF THE TAXANE CARBON FRAMEWORK [J].

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FURUKAWA, T ;

KUWAJIMA, I .

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[3] TAXOL - A NOVEL INVESTIGATIONAL ANTIMICROTUBULE AGENT [J].

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DONEHOWER, RC .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1990, 82 (15) :1247-1259

[4] TAXANE DITERPENE SYNTHESIS STRATEGIES - A REVIEW [J].

SWINDELL, CS .

ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, 1991, 23 (04) :465-543

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