A GENERAL-SYNTHESIS OF C2'-DEUTERIATED RIBONUCLEOSIDES

被引：30

作者：

COOK, GP ^{[1
]}

GREENBERG, MM ^{[1
]}

机构：

[1] COLORADO STATE UNIV,DEPT CHEM,FT COLLINS,CO 80523

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1994年 / 59卷 / 16期

关键词：

D O I：

10.1021/jo00095a060

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction sequence described above provides a concise, general synthesis of ribonucleosides that are isotopically enriched at C2′. Furthermore, 2′-deoxy-2′,2″-dideuteribonucleosides 11 are obtainable from [formula omitted] 6 via known methods which do not require separation of diastereomers following glycosidation.5,10a. © 1994, American Chemical Society. All rights reserved.

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页码：4704 / 4706

页数：3

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