POSSIBLE SOURCES OF IRON FOR LIPID-PEROXIDATION

被引:18
作者
MINOTTI, G
DIGENNARO, M
DUGO, D
GRANONE, P
机构
[1] UNIV CATTOLICA SACRO CUORE, SCH MED, INST GERIATR, I-00168 ROME, ITALY
[2] UNIV CATTOLICA SACRO CUORE, SCH MED, INST GEN SURG, I-00168 ROME, ITALY
来源
FREE RADICAL RESEARCH COMMUNICATIONS | 1991年 / 12-3卷
关键词
IRON; LIPID PEROXIDATION; FERRITIN; NONHEME-NONFERRITIN IRON; AGING; TUMORS;
D O I
10.3109/10715769109145773
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Possible sources of iron for lipid peroxidation are described and discussed. In particular. evidence is presented that microsomes contain ferric nonheme iron which may participate in formation of lipid oxidants. provided reductants are available to favor its mobilization from membrane binding sites. Aging-and tumor-associated changes of this microsomal pool of nonheme iron are also described and discussed from biochemical and biomedical viewpoints. © 1991 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
引用
收藏
页码:99 / 106
页数:8
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