EFFECT OF ENDURANCE TRAINING ON OXIDATION OF LACTATE IN MICE AFTER SUPRAMAXIMAL EXERCISE

The effect of endurance training on lactate metabolism after supramaximal exercise was investigated in male ddY mice. The blood lactate concentration 20 min after supramaximal exercise in the trained mice was significantly lower than that in the control mice. No significant effect of endurance training on the amount of (CO2)-C-14 expired from [C-14]lactate injected was found during the recovery period from supramaximal exercise. The muscle [C-14]glycogen concentration after 20 min of recovery in the trained mice was significantly higher than that in the control mice. These results suggest that endurance training does not enhance oxidative removal of lactate, which is the most important pathway of lactate metabolism, and activates muscle glycogen resynthesis from lactate in mice after supramaximal exercise.