CARDIOACTIVE EFFECTS OF EREMOPHILA-ALTERNIFOLIA EXTRACTS

被引：14

作者：

PENNACCHIO, M ^{[1
]}

ALEXANDER, E ^{[1
]}

GHISALBERTI, EL ^{[1
]}

RICHMOND, GS ^{[1
]}

机构：

[1] UNIV WESTERN AUSTRALIA,DEPT CHEM,NEDLANDS,WA 6009,AUSTRALIA

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 1995年 / 47卷 / 02期

关键词：

EREMOPHILA ALTERNIFOLIA; TRADITIONAL ABORIGINAL MEDICINES; CARDIOACTIVITY; LANGENDORFF HEART PREPARATION;

D O I：

10.1016/0378-8741(95)01258-F

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

An aqueous extract obtained from the leaves of the traditional Aboriginal medicinal plant Eremophila alternifolia R.Br. (Myoporaceae) was tested on isolated hearts of normotensive rats using the Langendorff heart preparation. A single injection of the extract into the retrograge perfusion solution induced cardioactivity, consisting of a short initial increase in force of contraction (positive inotropism), followed by a decrease in the force (negative inotropism) with simultaneous increase in heart;ate (positive chronotropism) and in coronary perfusion rate. These effects were not mediated by alpha- or beta-adrenergic receptors.

引用

页码：91 / 95

页数：5

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