ELASTIC FIBER DAMAGE INDUCED BY LOW-DOSE D-PENICILLAMINE

被引：16

作者：

DALZIEL, KL

BURGE, SM

FRITH, PA

RYAN, TJ

MOWAT, A

机构：

[1] SLADE HOSP, DEPT DERMATOL, OXFORD OX3 7JH, ENGLAND

[2] RADCLIFFE INFIRM, DEPT OPHTHALMOL, OXFORD OX2 6HE, ENGLAND

[3] NUFFIELD ORTHOPAED CTR, DEPT RHEUMATOL, OXFORD OX3 7LD, ENGLAND

来源：

BRITISH JOURNAL OF DERMATOLOGY | 1990年 / 123卷 / 03期

关键词：

D O I：

10.1111/j.1365-2133.1990.tb06289.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We have studied 23 patients receiving penicillamine for the treatment of rheumatoid arthritis to determine the prevalence of penicillamine-induced elastosis. One female patient had pseudoxanthoma elasticum-like skin changes and bramble-bush elastosis without calcification in the involved skin. Penicillamine elastosis was present in the joint capsule in 62% of eight patients or 64% of 11 joints examined and was detected in joint capsules after as little as 1 year of treatment.

引用

页码：305 / 312

页数：8

共 13 条

[1] LUMPY-BUMPY ELASTIC FIBERS IN THE SKIN AND LUNGS OF A PATIENT WITH A PENICILLAMINE-INDUCED ELASTOSIS PERFORANS SERPIGINOSA [J].