COLONY STIMULATING FACTORS, CYTOKINES AND MONOCYTE-MACROPHAGES - SOME CONTROVERSIES

被引：116

作者：

HAMILTON, JA

机构：

[1] University of Melbourne, Dept of Medicine, Royal Melbourne Hospital, Parkville

来源：

IMMUNOLOGY TODAY | 1993年 / 14卷 / 01期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/0167-5699(93)90319-G

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In the literature concerning induction of monocyte-macrophage inflammatory mediators in vitro by colony stimulating factors, IFN-gamma and TGF-beta, there are many conflicting observations; likewise there is disagreement when the regulation of the synthesis of colony stimulating factors by cytokines is examined. Here, John Hamilton attempts to identify unifying concepts from the conflicting data. He goes on to discuss the experimental variables that have led to the current confusion and to assess the significance of the in vitro studies to physiology and pathology.

引用

页码：18 / 24

页数：7

共 64 条

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