TRENDS IN THE SUSCEPTIBILITY OF TUBERCULOSIS IN NEW-YORK-CITY, 1987-1991

被引：32

作者：

SEPKOWITZ, KA

TELZAK, EE

RECALDE, S

ARMSTRONG, D

ATWOOD, E

BERGER, B

BERGER, J

BERKOWITZ, L

BLEVINS, A

BRASSEL, J

BROWN, A

BROWN, S

CHIRGWIN, K

CLARK, E

COLBY, S

CRUZ, E

CUNHA, B

DAVYDEEN, R

DECAPRARIIS, P

DELLALATTA, P

DHAR, S

DRUSIN, L

ELSADR, W

ERNST, J

FINE, J

GLASER, J

GORDON, M

GRIECO, M

HEWLETT, D

HOLZMAN, R

HOROWITZ, H

JENDRESKY, L

JENNY, L

JOHNSON, E

JORDAN, M

KALCUT, G

KAPLAN, M

KLEIN, N

LABOMBARDI, V

LANGE, M

LENOX, T

LERNER, C

LOURIA, D

LUTWICK, L

MCKINLEY, W

MAIR, E

MINUCCI, D

MURPHY, B

NEU, H

机构：

[1] Infectious Disease Service, Memorial Sloan-Kettering Cancer Center, New York, NY

[2] Infectious Disease Service, Memorial Sloan-Kettering Cancer Center, New York, NY

[3] Division oflnfectious Diseases, Bronx-Lebanon Hospital Center, Bronx, NY

来源：

CLINICAL INFECTIOUS DISEASES | 1994年 / 18卷 / 05期

关键词：

D O I：

10.1093/clinids/18.5.755

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The annual number of cases of tuberculosis in New York City has increased since 1978. In addition, in 1991 a 1-month survey of cases of tuberculosis in New York City found that 33% of all cases were resistant to at least one drug. To determine susceptibility trends from 1987 to 1991, a period during which an unprecedented rise in resistant tuberculosis occurred in New York City, we reviewed the microbiology records of 44 New York City hospitals (comprising > 14,000 cases). The percentage of cases resistant to at least one drug rose from 19% in 1987 to 28% in 1991, and the percentage of cases resistant to isoniazid rose from 13% in 1987 to 23% in 1991, while resistance to at least both isoniazid and rifampin rose from 6% to 14%. The rise of multidrug-resistant tuberculosis occurred in all four surveyed boroughs (counties) of New York City. These data demonstrate how rapidly multidrug-resistant tuberculosis can appear, and they suggest that initial empirical regimens should be broadened at certain hospitals.

引用

页码：755 / 759

页数：5

共 23 条

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