HEPATITIS-B MASS IMMUNIZATION OF ADOLESCENTS - A PILOT-STUDY IN A COMMUNITY

被引：11

作者：

PLAITANO, S ^{[1
]}

SAGLIOCCA, L ^{[1
]}

MELE, A ^{[1
]}

BOVE, C ^{[1
]}

PROTANO, D ^{[1
]}

ADAMO, B ^{[1
]}

PALUMBO, F ^{[1
]}

CAULETTI, M ^{[1
]}

FRANCO, E ^{[1
]}

PASQUINI, P ^{[1
]}

机构：

[1] IST SUPER SANITA,EPIDEMIOL & BIOSTAT LAB,VIALE REGINA ELENA 299,I-00161 ROME,ITALY

来源：

EUROPEAN JOURNAL OF EPIDEMIOLOGY | 1993年 / 9卷 / 03期

关键词：

HEPATITIS-B; IMMUNIZATION; ADOLESCENTS;

D O I：

10.1007/BF00146268

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The National Type Specific Hepatitis Surveillance System (SEIEVA) and seroepidemiological studies have shown that in addition to newborns from mothers who are carriers for hepatitis B surface antigen (HBsAg), adolescents are at high risk of acquiring type B hepatitis virus because of increasing importance of the heterosexual transmission of this virus. In order to evaluate logistic problems and acceptance rate of adolescents to mass vaccination against hepatitis B, a pilot study was carried out among all 7th grade children registered in the 9 schools of an hepatitis B endemic area located in the suburbs of Naples. After meetings held by the local health department with school teachers and parents, 1219 out of 1250 (97.5%) invited children received the first dose of hepatitis B vaccine; 1215 and 1209 received, respectively, the second and third doses. Anti-hepatitis B surface antigen (anti-HBs) values were studied in 406 subjects one month after the third dose, and 21 out of 406 (5.2%) had anti-HBs values less than 10 IU/L. We consider 95% of subjects with anti-HBs values greater than 9 IU/L a good achievement for a field vaccination program. The high acceptance rate of vaccination found in our study outlines the importance of active offer of vaccination combined with school involvement.

引用

页码：307 / 310

页数：4

共 10 条

[1]

D'Amelio R., Matricardi P.M., Biselli R., Changing epidemiology of hepatitis B in Italy: public health implications, Am. J. Epidemiol., 135, pp. 1012-1018, (1992)

[2]

D'Argenio P., Esposito D., Mele A., Decline in the exposure to hepatitis A and B infections in children in Naples, Italy, Public Health, 103, pp. 385-389, (1989)

[3]

Dardanoni L., Mele A., Polizzi M.C., Epidemiology of hepatitis B in Italy, Ann. Ist. Super. Sanita, 24, pp. 235-244, (1988)

[4]

Giusti G., Ruggiero G., Galanti B., Piccinino F., Sagnelli E., Gallo C., Chronic active hepatitis in Italy: a multicentric study, Hepato-Gastroenterology, 30, pp. 126-130, (1983)

[5]

Mele A., Stazi M.A., Corona R., Decline of incidence of A, B and Non-A Non-B Hepatitis in Italy. Results of four years surveillance (1985–1988), Ital. J. Gastroenterol., 22, pp. 274-280, (1990)

[6]

Pasquini P., Kahn H.A., Pileggi D., Pana A., Terzi I., Guzzanti E., Prevalence of hepatitis B markers in Italy, C. Am. J. Epidemiol., 118, pp. 699-709, (1983)

[7]

Pasquini P., Mele A., Stazi M.A., The importance of heterosexual transmission of hepatitis B in Italy, Proceedings of the “International Meeting on Hepatitis B: a sexually transmitted disease in heterosexuals” —Barcelona 7 May 1990, pp. 23-29, (1990)

[8]

Stroffolini T., Craxi' A., Gianmanco A., Hepatitis B virus infection in children in Palermo, Italy, J. Gastroenterol, 21, pp. 276-278, (1989)

[9]

Stroffolini T., Franco E., Romano G., Eur. J. Epidemiol., 5, pp. 202-206, (1989)

[10]

Stroffolini T., De Mattia D., Compagnone A., Arcamone G.P., Altomare M., Schettini F., Age-specific prevalence of hepatitis B virus infection among children in an endemic area in Southern Italy, Pediatr. Infect. Dis. J., 9, pp. 407-410, (1990)

← 1 →