DETERMINATION OF THE MOLECULAR LESIONS ASSOCIATED WITH LOSS-OF-FUNCTION TRANSFORMER ALLELES OF DROSOPHILA-MELANOGASTER

被引：3

作者：

YUAN, XQ ^{[1
]}

BELOTE, JM ^{[1
]}

机构：

[1] SYRACUSE UNIV,DEPT BIOL,BIOL RES LABS,SYRACUSE,NY 13244

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1995年 / 1260卷 / 03期

关键词：

MUTANT ALLELE; TRANSFORMER LOCUS; DNA SEQUENCE; NONSENSE MUTATION; (DROSOPHILA-MELANOGASTER);

D O I：

10.1016/0167-4781(94)00242-U

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three mutant alleles of the transformer locus, tra(v1), tra(v2) and tra(enu), were analyzed genetically, and all were found to be functionally null alleles. The DNA sequences of these mutants revealed that they represent nonsense mutations that potentially encode truncated Tra polypeptides of 12, 61, and 90 amino acids, respectively.

引用

页码：369 / 370

页数：2

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