KILLING OF DIFFERENT STRAINS OF TOXOPLASMA-GONDII TISSUE CYSTS BY IRRADIATION UNDER DEFINED CONDITIONS

被引：32

作者：

DUBEY, JP

THAYER, DW

机构：

[1] ARS, USDA, Eastern Regional Research Center, Philadelphia, PA 19118

来源：

JOURNAL OF PARASITOLOGY | 1994年 / 80卷 / 05期

关键词：

D O I：

10.2307/3283255

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

To study the effect of gamma-irradiation on the viability of Toxoplasma gondii tissue cysts, brains of mice inoculated with 95 newly isolated strains of T. gondii from pigs and 10 other laboratory isolates were pooled, flattened, packed in vacuum, and irradiated to absorbed doses of 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, and 0.9 kGy at 5 C (+/-0.5 C) with a Cs-137 gamma-radiation source. Treated samples were bioassayed for viable T. gondii in mice, cats, or both. Tissue cysts of all strains were rendered nonviable at 0.4 kGy. To study the effect of temperature on inactivation by irradiation, tissue cysts were irradiated at -4, 0, 4, 8, 12, and 16 C (+/-0.5 C) at 0.25 kGy. Temperature during irradiation had no marked effect on the viability of tissue cysts.

引用

页码：764 / 767

页数：4

共 20 条

[1]

Dubey J.P., 1988, TOXOPLASMOSIS ANIMAL

[2]

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[3]

DUBEY JP, 1986, AM J VET RES, V47, P518

[4]

DUBEY JP, 1980, AM J VET RES, V41, P427