AUTORADIOGRAPHIC ANALYSIS OF [ALPHA-BUNGAROTOXIN-H-3] DISTRIBUTION IN RAT-BRAIN AFTER INTRAVENTRICULAR-INJECTION

被引：51

作者：

SILVER, J ^{[1
]}

BILLIAR, RB ^{[1
]}

机构：

[1] CASE WESTERN RESERVE UNIV HOSP, DEPT REPROD BIOL, CLEVELAND, OH 44106 USA

来源：

JOURNAL OF CELL BIOLOGY | 1976年 / 71卷 / 03期

关键词：

D O I：

10.1083/jcb.71.3.956

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Purified .alpha.-bungarotoxin was isolated by chromatography and made radioactive with tritium ([3H]acetamidino-.alpha.-bungarotoxin). Infusions of [3H].alpha.-bungarotoxin alone or preceded by tubocurarine or atropine were given into the 3rd ventricle. Two 12 or 24 h after injection the brains were prepared for autoradiography. Injections of .alpha.-bungarotoxin (radioinert) in buffer, or of 3H parathyroid hormone in buffer, served as controls. The presence of nicotinic-cholinergic neurons within the arcuate and basolateral regions of the hypothalamus including the supraoptic and suprachiasmatic nuclei and, in addition, the central nucleus of the amygdala was suggested.

引用

页码：956 / 963

页数：8

共 31 条

[1] ARE MUSCARINIC RECEPTORS IN CENTRAL AND PERIPHERAL NERVOUS-SYSTEM DIFFERENT [J].

BELD, AJ ;

VANDENHOVEN, S ;

WOUTERSE, AC ;

ZEGERS, MAP .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1975, 30 (02) :360-363

[2] EFFECTS OF HYPOTHALAMIC DEAFFERENTATION ON PULSATILE RHYTHM IN PLASMA CONCENTRATIONS OF LUTEINIZING-HORMONE IN OVARIECTOMIZED RATS [J].

BLAKE, CA ;

SAWYER, CH .

ENDOCRINOLOGY, 1974, 94 (03) :730-736

[3] FINE-STRUCTURE OF EPENDYMAL TANYCYTES AT LEVEL OF ARCUATE NUCLEUS [J].

BRAWER, JR .

JOURNAL OF COMPARATIVE NEUROLOGY, 1972, 145 (01) :25-+

[4] DISTRIBUTION WITHIN BRAIN OF FERRITIN INJECTED INTO CEREBROSPINAL FLUID COMPARTMENTS .I. EPENDYMAL DISTRIBUTION [J].

BRIGHTMA.MW .

JOURNAL OF CELL BIOLOGY, 1965, 26 (01) :99-+

[5] ACETYLCHOLINE RECEPTORS IN NORMAL AND DENERVATED RAT DIAPHRAGM MUSCLE .1. PURIFICATION AND INTERACTION WITH [I-125]-ALPHA-BUNGAROTOXIN [J].

BROCKES, JP ;

HALL, ZW .

BIOCHEMISTRY, 1975, 14 (10) :2092-2099

[6]

CHANG CC, 1963, ARCH INT PHARMACOD T, V144, P241

[7] USE OF A SNAKE VENON TOXIN TO CHARACTERIZE CHOLINERGIC RECEPTOR PROTEIN [J].

CHANGEUX, JP ;

KASAI, M ;

LEE, CY .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1970, 67 (03) :1241-+

[8] CHEMOGRAPHY ASSOCIATED WITH SPECIFIC ANATOMIC AREAS IN AUTORADIOGRAPHS OF BRAIN STEMS FROM ADULT RATS [J].

DANIELS, JS ;

GILMORE, SA .

BRAIN RESEARCH, 1975, 98 (02) :343-347

[9] CHEMICAL SENSITIVITY OF PREOPTIC NEURONS WHICH PROJECT TO MEDIAL BASAL HYPOTHALAMUS [J].

DYBALL, REJ ;

DYER, RG ;

DREWETT, RF .

BRAIN RESEARCH, 1974, 71 (01) :140-143

[10] NICOTINIC CHOLINERGIC RECEPTOR IN BRAIN DETECTED BY BINDING OF ALPHA-[H-3]BUNGAROTOXIN [J].

ETEROVIC, VA ;

BENNETT, EL .

BIOCHIMICA ET BIOPHYSICA ACTA, 1974, 362 (02) :346-355

← 1 2 3 4 →