SPIROCHETES IN EARLY LESIONS OF NECROTIZING ULCERATIVE GINGIVITIS EXPERIMENTALLY INDUCED IN BEAGLES

被引：20

作者：

MIKX, FHM

MALTHA, JC

VANCAMPEN, GJ

机构：

[1] Department of Periodontology and Preventive Dentistry, University of Nijmegen

[2] Laboratory of Oral Histology, University of Nijmegen

来源：

ORAL MICROBIOLOGY AND IMMUNOLOGY | 1990年 / 5卷 / 02期

关键词：

invasion; spirochetes; ulcerative gingivitis;

D O I：

10.1111/j.1399-302X.1990.tb00233.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

The presence of Spirochetes and other bacteria during the induction of necrotizing ulcerative gingivitis (NUG) in beagle dogs was studied by transmission electron microscopy. NUG was induced by application of dental debris from diseased dogs to 4 beagles treated with corticosteroid. Biopsies of interdental papillae were collected during a period of 7 weeks. Spirochetes and other bacteria were observed in enlarged intercellular spaces between non‐keratinized epithelial cells. Intracellular bacteria were found with and without surrounding vesicular spaces. The invasive Spirochetes were mainly intermediately sized and of flagellar “4‐8‐4” configuration or higher. Bacterial invasion of the sulcular epithelium occurred before clinical evidence of NUG could be observed. It is concluded that invasion by intermediate spirochetes and other bacteria plays a role in initiating ulcerative gingivitis in beagles. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：86 / 89

页数：4

共 18 条

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