FLUCONAZOLE-INDUCED TOXIC EPIDERMAL NECROLYSIS IN A PATIENT WITH HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION

被引：23

作者：

AZONMASOLIVER, A ^{[1
]}

VILAPLANA, J ^{[1
]}

机构：

[1] HOSP ST JOAN,DEPT DERMATOL,REUS,SPAIN

来源：

DERMATOLOGY | 1993年 / 187卷 / 04期

关键词：

FLUCONAZOLE; HUMAN IMMUNODEFICIENCY VIRUS; TOXIC EPIDERMAL NECROLYSIS;

D O I：

10.1159/000247261

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Patients with human immunodeficiency virus (HIV) infection are prone to severe drug reactions, mainly from sulfonamides. We report the case of a 33-year-old male patient with HIV infection (group IV C-2 of CDC staging system) that developed a toxic epidermal necrolysis (TEN) affecting more than 70% of the body surface area and severe mucosal involvement after starting fluconazole for a recurrent oral thrush with dysphagia. This is to our knowledge the first reported case of TEN due to fluconazole.

引用

页码：268 / 269

页数：2

共 7 条

[1]

ABBOTT M, 1991, LANCET, V331, P633

[2] FLUCONAZOLE, A NEW ANTIFUNGAL AGENT [J].