USE OF TRICHLORODIMETHYLETHYL AS A PROTECTING GROUP AND TRIBUTYLPHOSPHINE AS A DE-PROTECTING AGENT IN OLIGONUCLEOTIDE SYNTHESIS

被引：44

作者：

LETSINGER, RL

GROODY, EP

TANAKA, T

机构：

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1982年 / 104卷 / 24期

关键词：

D O I：

10.1021/ja00388a066

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

收藏

页码：6805 / 6806

页数：2

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共 16 条

[1] ALVARADOURBINA G, 1981, SCIENCE WASHINGTON, V270
[2] DEOXYNUCLEOSIDE PHOSPHORAMIDITES - A NEW CLASS OF KEY INTERMEDIATES FOR DEOXYPOLYNUCLEOTIDE SYNTHESIS
BEAUCAGE, SL
CARUTHERS, MH
[J]. TETRAHEDRON LETTERS, 1981, 22 (20) : 1859 - 1862
[3] SYNTHESIS OF OLIGODEOXYRIBONUCLEOTIDES ON SILICA-GEL SUPPORT
CHOW, F
KEMPE, T
PALM, G
[J]. NUCLEIC ACIDS RESEARCH, 1981, 9 (12) : 2807 - 2817
[4] FRAGMENTATIONS WITH SUPERNUCLEOPHILES .7. 2,2,2-TRICHLORO-TERT-BUTYLOXYCARBONYL GROUP (TCBOC) - ACID-RESISTANT AND BASE-RESISTANT PROTECTING GROUP REMOVABLE UNDER MILD CONDITIONS
ECKERT, H
LISTL, M
UGI, I
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1978, 17 (05): : 361 - 362
[5] SYNTHESIF OF OLIGONUCLEOTIDES BY USE OF PHOSPHORIC TRIESTERS
ECKSTEIN, F
RIZK, I
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1967, 6 (08) : 695 - &
[6] FINNAN JL, 1980, NUCL ACIDS RES S SER, V7, P133
[7] GERRARD W, 1949, Research, V2, P536
[8] SYNTHESIS OF THYMIDINE OLIGONUCLEOTIDES BY PHOSPHITE TRIESTER INTERMEDIATES
LETSINGER, RL
LUNSFORD, WB
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (12) : 3655 - 3661
[9] NUCLEOTIDE CHEMISTRY .20. PHOSPHITE COUPLING PROCEDURE FOR GENERATING INTERNUCLEOTIDE LINKS
LETSINGER, RL
FINNAN, JL
HEAVNER, GA
LUNSFORD, WB
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1975, 97 (11) : 3278 - 3279
[10] SELECTIVE DEPROTECTION BY REDUCTIVE CLEAVAGE WITH RADICAL-ANIONS
LETSINGER, RL
FINNAN, JL
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1975, 97 (24) : 7197 - 7198