DETERMINATION OF PYRIMETHAMINE AND SULFADIMETHOXINE RESIDUES IN EGGS BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

被引:16
作者
NAGATA, T [1 ]
SAEKI, M [1 ]
IIDA, T [1 ]
KATAOKA, M [1 ]
SHIKANO, S [1 ]
机构
[1] CHIBA PREFECTURE LIVESTOCK EXPTL STN,INBAGUN,CHIBA,JAPAN
关键词
D O I
10.1080/00071669208417539
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
1. Laying hens were given food containing per kg diet: 1 mg pyrimethamine, 10 mg sulphadimethoxine (SDM) or 1 mg pyrimethamine with 10 mg SDM, for 14 days. Residues in the eggs were determined by high performance liquid chromatography. 2. Pyrimethamine was mainly found in yolk. Its concentration was slightly higher when it was given with SDM. 3. The concentrations of SDM in eggs were not different when it was given alone or in combination with pyrimethamine. 4. After withdrawal, pyrimethamine residues decreased below the detection limit (0.02 mg/kg) in the yolk after 11 to 12 d and in the albumen after 2 to 3 d. SDM in yolk fell below the detection limit (0.01 mg/kg) on day 7, whereas in albumen it was not detectable after 2 to 3 d.
引用
收藏
页码:953 / 961
页数:9
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