GROWTH-INHIBITORY RESPONSES OF HUMAN INTESTINAL BACTERIA TO EXTRACTS OF ORIENTAL MEDICINAL-PLANTS

被引：17

作者：

AHN, YJ

KWON, JH

CHAE, SH

PARK, JH

YOO, JY

机构：

[1] SEOUL NATL UNIV, NEW BIOMAT AGR RES CTR, SUWON 441744, SOUTH KOREA

[2] KOREA FOOD RES INST, SUNGNAM 462420, SOUTH KOREA

来源：

MICROBIAL ECOLOGY IN HEALTH AND DISEASE | 1994年 / 7卷 / 05期

关键词：

ORIENTAL MEDICINAL PLANTS; INTESTINAL BACTERIA; GROWTH INHIBITION; BIFIDOBACTERIUM ADOLESCENTIS; CLOSTRIDIUM PERFRINGENS; ESCHERICHIA COLI;

D O I：

10.3109/08910609409141363

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Methanol extracts from 50 species of oriental medicinal plants were prepared and subjected to an in vitro screening test for their growth-inhibitory activity towards Bifidobacterium adolescentis, Clostridium perfringens and Escherichia coli, using a paper disc agar diffusion method under O-2-free conditions. The inhibitory activity was both bacteria and plant-species dependent. Extracts from Pueraria thumbergiana, Astragalus membranaceus, Eucommia ulmoides, Coptis japonica, Akebia quinata and Rhus chinensis strongly inhibited growth of C. perfringens. A growth-inhibitory effect against E. coli was observed from extracts of C. japonica. These plant extracts did not affect the growth of B. adolescentis. It is concluded that intake of these oriental medicinal plants may be important in the prevention of human diseases caused by intestinal microorganisms by altering the growth and composition of intestinal bacteria and modulating the genesis of potentially harmful metabolites.

引用

页码：257 / 261

页数：5

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