DIFFERENTIATION OF SENSORIMOTOR NEURONAL STRUCTURES RESPONSIBLE FOR INDUCTION OF MOTOR EVOKED-POTENTIALS, ATTENUATION IN DETECTION OF SOMATOSENSORY STIMULI, AND INDUCTION OF SENSATION OF MOVEMENT BY MAPPING OF OPTIMAL CURRENT DIRECTIONS

被引:37
作者
PASCUALLEONE, A [1 ]
COHEN, LG [1 ]
BRASILNETO, JP [1 ]
VALLSSOLE, J [1 ]
HALLETT, M [1 ]
机构
[1] NINCDS,MED NEUROL BRANCH,HUMAN MOTOR CONTROL SECT,HUMAN CORT PHYSIOL UNIT,BETHESDA,MD 20892
来源
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY | 1994年 / 93卷 / 03期
关键词
MOTOR CORTEX; SENSORY CORTEX; TRANSCRANIAL MAGNETIC STIMULATION; CURRENT DIRECTION; VECTOR; PHYSIOLOGY; ELECTROMYOGRAPHY (EMG); (HUMAN);
D O I
10.1016/0168-5597(94)90045-0
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Transcranial magnetic stimulation (TMS) of the sensorimotor cortex can evoke motor evoked potentials (MEPs), attenuation in detection of somatosensory stimuli (ADSS), and sensation of movement (SOM) referred to the same body part. In this study we tried to differentiate the substrates responsible for these effects. In 6 normal volunteers; TMS was applied with a nearly monopolar Dantec stimulator and a butterfly coil. Optimal scalp location and current direction were determined for induction of MEPs in abductor pollicis brevis (APB), first dorsal interosseous (FDI), and adductor digiti minimi (ADM); SOM in digits 2 and 5 in an ischemically paralyzed hand; and ADSS applied to digits 2 and 5. All 3 muscles' MEPs and SOM and ADSS in both digits were optimally activated from a single scalp position. In all subjects, optimal current directions for MEPs pointed anteriorly; those for ADSS and SOM pointed posteriorly. Optimal current directions showed the same progression in all subjects for MEPs (ADM, FDI, and APB from antero-lateral to antero-medial), ADSS (digit 5 postero-medial, 2 postero-lateral), and SOM (digit 1 through 5 postero-lateral to postero-medial). We conclude that neuronal networks targeting corticospinal neurons responsible for MEPs are different from those leading to SOM and ADSS (which could not be differentiated).
引用
收藏
页码:230 / 236
页数:7
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