STUDY OF TRACE-ELEMENTS IN BLOOD OF CANCER-PATIENTS BY PROTON-INDUCED X-RAY-EMISSION (PIXE) ANALYSIS

被引:7
作者
DUROSINMI, MA
OJO, JO
OLUWOLE, AF
AKANLE, OA
SPYROU, NM
机构
[1] OBAFEMI AWOLOWO UNIV, DEPT HAEMATOL, IFE, NIGERIA
[2] OBAFEMI AWOLOWO UNIV, DEPT PHYS, IFE, NIGERIA
[3] UNIV SURREY, DEPT PHYS, GUILDFORD GU2 5XH, SURREY, ENGLAND
关键词
TRACE ELEMENTS; PLASMA; ERYTHROCYTES; CANCER; PIXE ANALYSIS;
D O I
10.1007/BF02917335
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Proton-induced X-ray emission (PIXE) analysis was employed to determine the concentrations of six elements in the plasma and erythrocytes of 18 cancer subjects (15 males and 3 females) with neoplastic disorders and in 70 controls (35 males and 35 females). It was found that the concentrations of Br, K, and Zn were significantly elevated in the erythrocytes of the cancer subjects compared to the controls, whereas the concentration of Fe was significantly depressed, but with no difference observed in the concentration of Ca. In the plasma, the concentrations of Br, Cu, Ca, and K were significantly elevated, whereas the concentrations of Fe and Zn were found to be significantly depressed compared to the controls.
引用
收藏
页码:351 / 355
页数:5
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