ULTRASTRUCTURAL PATHOLOGY OF THE BARRIER SITES IN EXPERIMENTAL AUTOIMMUNE UVEITIS AND EXPERIMENTAL AUTOIMMUNE PINEALITIS

被引：34

作者：

DUA, HS

MCKINNON, A

MCMENAMIN, PG

FORRESTER, JV

机构：

[1] UNIV ABERDEEN,DEPT OPHTHALMOL,ABERDEEN AB9 1FX,SCOTLAND

[2] UNIV ABERDEEN,DEPT PATHOL,ABERDEEN AB9 1FX,SCOTLAND

[3] UNIV PERTH,DEPT ANAT & HUMAN BIOL,PERTH,WA,AUSTRALIA

来源：

BRITISH JOURNAL OF OPHTHALMOLOGY | 1991年 / 75卷 / 07期

关键词：

D O I：

10.1136/bjo.75.7.391

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Lewis rats were immunised with retinal S-antigen to induce experimental autoimmune uveitis and experimental autoimmune pinealitis. The blood-retinal and blood-pineal 'barrier sites' were examined by transmission electron microscopy. Inflammatory cell movement through Bruch's membrane involved separation of its constituent layers, cell migration through pores in the membrane, and between retinal pigment epithelial cells without causing significant displacement of the retinal pigment epithelial cell layer. The endothelial cells of retinal and pineal vessels with perivascular infiltrates showed morphological features resembling endothelium of 'high endothelial venules'.

引用

页码：391 / 397

页数：7

共 15 条

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