1ST PRENATAL-DIAGNOSIS OF X-LINKED LYMPHOPROLIFERATIVE DISEASE

被引：5

作者：

SKARE, J

MADAN, S

GLASER, J

PURTILO, D

NITOWSKY, H

PULIJAAL, V

MILUNSKY, A

机构：

[1] YESHIVA UNIV ALBERT EINSTEIN COLL MED, DEPT OBSTET & GYNECOL, BRONX, NY 10461 USA

[2] YESHIVA UNIV ALBERT EINSTEIN COLL MED, DEPT PEDIAT, BRONX, NY 10461 USA

[3] BOSTON UNIV, SCH MED, DEPT PEDIAT, BOSTON, MA 02118 USA

[4] BOSTON UNIV, SCH MED, DEPT PATHOL & MICROBIOL, BOSTON, MA 02118 USA

[5] UNIV NEBRASKA, MED CTR, DEPT PATHOL, OMAHA, NE 68105 USA

[6] UNIV NEBRASKA, MED CTR, DEPT MICROBIOL, OMAHA, NE 68105 USA

来源：

AMERICAN JOURNAL OF MEDICAL GENETICS | 1992年 / 44卷 / 01期

关键词：

X-LINKED LYMPHOPROLIFERATIVE DISEASE; X-CHROMOSOME RFLP; IMMUNODEFICIENCY; PRENATAL DIAGNOSIS;

D O I：

10.1002/ajmg.1320440119

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A family study was performed in order to diagnose X-linked lymphoproliferative (XLP) disease in a fetus. The molecular genetic analysis indicated that the fetus, as well as its healthy 7-year-old brother, inherited XLP. Analysis of immunoglobulin subclasses from the 7-year-old brother supported the DNA-based diagnosis. This is the first XLP family of African descent.

引用

页码：79 / 81

页数：3

共 11 条

[1] EPSTEIN-BARR VIRUS-INFECTIONS IN MALES WITH THE X-LINKED LYMPHOPROLIFERATIVE SYNDROME [J].