COMPARISON OF PREGNANCY RATES FOLLOWING INVITRO FERTILIZATION EMBRYO TRANSFER BETWEEN THE DONORS AND THE RECIPIENTS IN A DONOR OOCYTE PROGRAM

被引：43

作者：

CHECK, JH

NOWROOZI, K

CHASE, J

NAZARI, A

BRAITHWAITE, C

机构：

[1] UNIV MED & DENT NEW JERSEY,COOPER HOSP UNIV MED CTR,ROBERT WOOD JOHNSON MED SCH,DEPT OB GYN,CAMDEN,NJ

[2] ENDOCRINE HISTOL ASSOCIATES,MELROSE PK,PA

来源：

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS | 1992年 / 9卷 / 03期

关键词：

DONOR OOCYTE; RECIPIENTS; HYPERSTIMULATION REGIMEN; PREGNANCY RATES;

D O I：

10.1007/BF01203822

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Our in vitro fertilization (IVF) program provides a unique opportunity to evaluate influences of hormonal milieu on pregnancy outcome, by using a shared pool of oocytes obtained by donors (in exchange for financial assistance). The study presented herein evaluated 38 retrieval cycles (28 oocyte donors/22 recipients). No difference in mean number of embryos transferred was seen (2.7 in the donors vs 2.8 in the recipients). However, a statistically significant difference was seen in the pregnancy rates per retrieval (10.5% donors vs 29% recipients) and per transfer (4/35, 11.1%, vs 11/34, 32.3%). Abortion rates were similar (25% donor, 27.2% recipients). These data suggest that other reports of higher pregnancy rates from donor oocyte programs may not be due exclusively to better-quality oocytes. Possibly a negative effect of hyperstimulation or adverse endometrial environment of the donor (possible chronic endometritis) may explain these data.

引用

页码：248 / 250

页数：3

共 4 条

[1]

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[2]

Ben-Nun I., Ghetler Y., Gruber A., Jaffe R., Fejgin M., Egg donation in an in vitro fertilization program: An alternative approach to cycle synchronization and timing of embryo transfer, Fertil Steril, 52, pp. 683-687, (1989)

[3]

Borrero C., Remohi J., Ord T., Balmaceda J.P., Rojas F., Asch R.H., A program of oocyte donation and gamete intra-fallopian transfer, Hum Reprod, 4, 3, pp. 275-279, (1989)

[4]

Meldrum D.R., Wisot A., Hamilton F., Gutlay A.L., Kempton W., Huynh D., Routine pituitary suppression with leuprolide before ovarian stimulation for oocyte retrieval, Fertil Steril, 51, pp. 455-459, (1989)

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