DIASTEREOSELECTIVE CONDENSATION OF OXAZAPHOSPHITES WITH ALIPHATIC AND AROMATIC-ALDEHYDES

被引：56

作者：

GORDON, NJ ^{[1
]}

EVANS, SA ^{[1
]}

机构：

[1] UNIV N CAROLINA, WILLIAM RAND KENAN JR LABS CHEM, CB 3290, CHAPEL HILL, NC 27599 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1993年 / 58卷 / 20期

关键词：

D O I：

10.1021/jo00072a002

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The results of a preliminary investigation involving the condensations of diastereomeric 2-methoxy-1,3,2-oxazaphosphites (cis- and trans-5) with a variety of aldehyde-boron trifluoride etherate (BF3.Et2O) complexes to give disatereomerically-enriched mixtures of alpha-hydroxy-2-oxo-1,3,2-oxazaphosphorinanes (cis- and trans-3 and 4) are reported, and a mechanistic rationale consistent with the diastereofacial preference attending these reactions is proposed.

引用

页码：5293 / 5294

页数：2

共 12 条

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