SYNTHESIS OF NEW CHIRAL PHOSPHINEPHOSPHITES HAVING 2-DIPHENYLPHOSPHINOBIPHENYL-2'-YL BACKBONE AND THEIR USE IN RH(I)-CATALYZED ASYMMETRIC HYDROFORMYLATIONS

被引:85
作者
HIGASHIZIMA, T [1 ]
SAKAI, N [1 ]
NOZAKI, K [1 ]
TAKAYA, H [1 ]
机构
[1] KYOTO UNIV,FAC ENGN,DIV MAT CHEM,SAKYO KU,KYOTO 60601,JAPAN
关键词
D O I
10.1016/S0040-4039(00)73039-5
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
New chiral phosphinephosphites (R)-(5,5'-dichloro-2-diphenylphosphino-4,4',6,6'-tetramethylbiphenyl-2'-yl)((S)-1,1'-binaphthalen-2,2'-diyl)phosphite [abbreviated (R,S)-BIPHEMPHOS] and its enantiomer (S,R)-BIPHEMPHOS have been synthesized from 5,5'-dichloro-4,4',6,6'-tetramethyl-2,2'-biphenyldiol in enantiomerically pure form. Their Rh(I) complexes have been shown to be highly efficient catalysts for asymmetric hydroformylations of a variety of olefinic substrates. The corresponding phosphinephosphites derived from 2,2'-biphenyldiol were also tested as ligands for asymmetric hydroformylation.
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页码:2023 / 2026
页数:4
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