SULFUR AMINO-ACID-METABOLISM IN SCHIZOSACCHAROMYCES-POMBE - OCCURRENCE OF 2 O-ACETYLHOMOSERINE SULFHYDRYLASES AND THE LACK OF THE REVERSE TRANSSULFURATION PATHWAY

被引：19

作者：

BRZYWCZY, J ^{[1
]}

PASZEWSKI, A ^{[1
]}

机构：

[1] INST BIOCHEM & BIOPHYS,PL-02106 WARSAW,POLAND

来源：

FEMS MICROBIOLOGY LETTERS | 1994年 / 121卷 / 02期

关键词：

SCHIZOSACCHAROMYCES POMBE; SULFUR METABOLISM;

D O I：

10.1016/0378-1097(94)90123-6

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The fission yeast Schizosaccharomyces pombe has a unique organization of sulfur amino acid metabolism: it has two distinct O-acetylhomoserine sulfhydrylases (homocysteine synthases). Similar to Enterobacteriaceae, S. pombe lacks cystathionine beta-synthase and cystathionine gamma-lyase - the enzymes of the reverse transsulfuration pathway, by which methionine is readily metabolized to cysteine - a likely effector in the sulfur metabolite repression system. Consequently no repression of sulfate assimilation is observed when methionine is added to the growth medium.

引用

页码：171 / 174

页数：4

共 12 条

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