LONG-TERM SURVIVORS OF HIV-1 INFECTION

被引：57

作者：

KLEIN, MR

MIEDEMA, F

机构：

[1] NETHERLANDS RED CROSS,BLOOD TRANSFUS SERV,CENT LAB,DEPT CLIN VIROIMMUNOL,1066 CX AMSTERDAM,NETHERLANDS

[2] UNIV AMSTERDAM,EXPTL & CLIN IMMUNOL LAB,1066 CX AMSTERDAM,NETHERLANDS

来源：

TRENDS IN MICROBIOLOGY | 1995年 / 3卷 / 10期

关键词：

D O I：

10.1016/S0966-842X(00)88984-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The clinical course and outcome of HIV-1 infection are highly variable. A full spectrum of pathology has been observed, from rapid progression to AIDS within months of HIV-1 seroconversion, to asymptomatic survival for more than a decade. This phenomenon probably reflects the multiphasic and multifactorial nature of the virus-host interactions. Obviously, interest in the extremes now recognized in HIV-1 disease progression is growing, with the hope that mechanisms of protection may be found.

引用

收藏

页码：386 / 391

页数：6

相关论文

共 53 条

[1] VIRUS-SPECIFIC CD8+ CYTOTOXIC T-LYMPHOCYTE ACTIVITY ASSOCIATED WITH CONTROL OF VIREMIA IN PRIMARY HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 INFECTION [J].

BORROW, P ;

LEWICKI, H ;

HAHN, BH ;

SHAW, GM ;

OLDSTONE, MBA .

JOURNAL OF VIROLOGY, 1994, 68 (09) :6103-6110

[2] CLEARANCE OF HIV-INFECTION IN A PERINATALLY INFECTED INFANT [J].

BRYSON, YJ ;

PANG, S ;

WEI, LS ;

DICKOVER, R ;

DIAGNE, A ;

CHEN, ISY .

NEW ENGLAND JOURNAL OF MEDICINE, 1995, 332 (13) :833-838

[3] LONG-TERM HIV-1 INFECTION WITHOUT IMMUNOLOGICAL PROGRESSION [J].

BUCHBINDER, SP ;

KATZ, MH ;

HESSOL, NA ;

OMALLEY, PM ;

HOLMBERG, SD .

AIDS, 1994, 8 (08) :1123-1128

[4] VIROLOGICAL AND IMMUNOLOGICAL CHARACTERIZATION OF LONG-TERM SURVIVORS OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 INFECTION [J].

CAO, YZ ;

QIN, LM ;

ZHANG, LQ ;

SAFRIT, J ;

HO, DD .

NEW ENGLAND JOURNAL OF MEDICINE, 1995, 332 (04) :201-208

[5] HIV-SPECIFIC T-HELPER ACTIVITY IN SERONEGATIVE HEALTH-CARE WORKERS EXPOSED TO CONTAMINATED BLOOD [J].

CLERICI, M ;

LEVIN, JM ;

KESSLER, HA ;

HARRIS, A ;

BERZOFSKY, JA ;

LANDAY, AL ;

SHEARER, GM .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1994, 271 (01) :42-46

[6] CELL-MEDIATED IMMUNE-RESPONSE TO HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) TYPE-1 IN SERONEGATIVE HOMOSEXUAL MEN WITH RECENT SEXUAL EXPOSURE TO HIV-1 [J].

CLERICI, M ;

GIORGI, JV ;

CHOU, CC ;

GUDEMAN, VK ;

ZACK, JA ;

GUPTA, P ;

HO, HN ;

NISHANIAN, PG ;

BERZOFSKY, JA ;

SHEARER, GM .

JOURNAL OF INFECTIOUS DISEASES, 1992, 165 (06) :1012-1019

[7] TRANSMISSION AND PATHOGENESIS OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 [J].

CONNOR, RI ;

HO, DD .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 1994, 10 (04) :321-323

[8] INCREASED VIRAL BURDEN AND CYTOPATHICITY CORRELATE TEMPORALLY WITH CD4+ T-LYMPHOCYTE DECLINE AND CLINICAL PROGRESSION IN HUMAN-IMMUNODEFICIENCY-VIRUS TYPE 1-INFECTED INDIVIDUALS [J].

CONNOR, RI ;

MOHRI, H ;

CAO, YZ ;

HO, DD .

JOURNAL OF VIROLOGY, 1993, 67 (04) :1772-1777

[9] PROTECTIVE EFFECTS OF A LIVE ATTENUATED SIV VACCINE WITH A DELETION IN THE NEF GENE [J].

DANIEL, MD ;

KIRCHHOFF, F ;

CZAJAK, SC ;

SEHGAL, PK ;

DESROSIERS, RC .

SCIENCE, 1992, 258 (5090) :1938-1941

[10] OCCURRENCE OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV-1)-SPECIFIC CYTOLYTIC T-CELL ACTIVITY IN APPARENTLY UNINFECTED CHILDREN BORN TO HIV-1-INFECTED MOTHERS [J].

DEMARIA, A ;

CIRILLO, C ;

MORETTA, L .

JOURNAL OF INFECTIOUS DISEASES, 1994, 170 (05) :1296-1299

← 1 2 3 4 5 6 →