PRIMARY STRUCTURE AND FUNCTIONAL EXPRESSION OF A HIGH-VOLTAGE ACTIVATED CALCIUM-CHANNEL FROM RABBIT LUNG

被引:215
作者
BIEL, M
RUTH, P
BOSSE, E
HULLIN, R
STUHMER, W
FLOCKERZI, V
HOFMANN, F
机构
[1] UNIV SAARLAND,W-6650 HOMBURG,GERMANY
[2] MAX PLANCK INST BIOPHYS CHEM,W-3400 GOTTINGEN,GERMANY
关键词
Ca[!sup]2+[!/sup] channel; Expression; Primary structure; Smooth muscle;
D O I
10.1016/0014-5793(90)81205-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The complete amino acid sequence of the receptor for organic calcium channel blockers (CaCB) from rabbit lung has been deduced by cloning and sequence analysis of the cDNA. Synthetic RNA derived from this cDNA induces the formation of a functional CaCB-sensitive high voltage activated calcium channel in Xenopus oocytes. © 1990.
引用
收藏
页码:409 / 412
页数:4
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