4-(PHOSPHONOALKYL)-2-PIPERIDINECARBOXYLIC AND 4-(PHOSPHONOALKENYL)-2-PIPERIDINECARBOXYLIC ACIDS - SYNTHESIS, ACTIVITY AT N-METHYL-D-ASPARTIC ACID RECEPTORS, AND ANTICONVULSANT ACTIVITY

被引：91

作者：

HUTCHISON, AJ

WILLIAMS, M

ANGST, C

DEJESUS, R

BLANCHARD, L

JACKSON, RH

WILUSZ, EJ

MURPHY, DE

BERNARD, PS

SCHNEIDER, J

CAMPBELL, T

GUIDA, W

SILLS, MA

机构：

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 09期

关键词：

D O I：

10.1021/jm00129a025

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：2171 / 2178

页数：8

共 24 条

[1]

ANGST C, UNPUB

[2] SYNTHESIS AND STABILITY OF 2-METHYL-2,4-DIAZA-INDENE AND 2-METHYL-2,5-DIAZA-INDENE + (2-METHYL-PYRROLO[3,4-B]PYRIDINE AND PYRROLO[3,4-C]PYRIDINE) [J].

ARMAREGO, WL ;

MILLOY, BA ;

SHARMA, SC .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1972, (20) :2485-&

[3]

BENNETT DA, IN PRESS J PHARM EXP

[4] EXCITATORY AMINO-ACIDS IN THE BRAIN - FOCUS ON NMDA RECEPTORS [J].

COTMAN, CW ;

IVERSEN, LL .

TRENDS IN NEUROSCIENCES, 1987, 10 (07) :263-265

[5]

Finney D. J, 1962, PROBIT ANAL

[6] ON THE EXCITOTOXIC PROPERTIES OF QUINOLINIC ACID, 2,3-PIPERIDINE DICARBOXYLIC-ACIDS AND STRUCTURALLY RELATED-COMPOUNDS [J].

FOSTER, AC ;

COLLINS, JF ;

SCHWARCZ, R .

NEUROPHARMACOLOGY, 1983, 22 (12) :1331-&

[7] THE NOVEL N-METHYL-D-ASPARTATE (NMDA) ANTAGONIST CGS-19755 PREVENTS ISCHEMIA-INDUCED REDUCTIONS OF ADENOSINE-A1, NMDA, AND PCP RECEPTORS IN GERBIL BRAIN [J].

JARVIS, MF ;

MURPHY, DE ;

WILLIAMS, M ;

GERHARDT, SC ;

BOAST, CA .

SYNAPSE, 1988, 2 (06) :577-584

[8]

LEHMANN J, 1987, ANNU REP MED CHEM, V22, P31

[9]

LEHMANN J, 1988, J PHARMACOL EXP THER, V246, P65

[10] THE MULTIPLE MINIMUM PROBLEM IN MOLECULAR MODELING - TREE SEARCHING INTERNAL COORDINATE CONFORMATIONAL SPACE [J].

LIPTON, M ;

STILL, WC .

JOURNAL OF COMPUTATIONAL CHEMISTRY, 1988, 9 (04) :343-355

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