STEREOSELECTIVE ALKYLATIONS OF CHIRAL, PHOSPHORUS-STABILIZED BENZYLIC CARBANIONS

被引：62

作者：

DENMARK, SE

DOROW, RL

机构：

[1] Roger Adams Laboratory, Department of Chemistry, University of Illinois, Urbana

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 24期

关键词：

D O I：

10.1021/jo00311a003

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

: A series of 6-substituted 2-benzyl-3-tert-bu-tyl-1,3,2-oxazaphosphorinanes was prepared in racemic and enantiomerically pure form. The diastereoselectivity of alkylation of the derived anions was examined as a function of ring substitution pattern, base, solvent, electrophile, and enantiomeric composition. © 1990, American Chemical Society. All rights reserved.

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页码：5926 / 5928

页数：3

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