CHRONIC ACQUIRED IMMUNODEFICIENCY SYNDROME-ASSOCIATED ARTHRITIS - A SYNOVIAL ULTRASTRUCTURAL-STUDY

被引：32

作者：

BENTIN, J

FEREMANS, W

PASTEELS, JL

HAUZEUR, JP

MENU, R

APPELBOOM, T

机构：

[1] UNIV BRUSSELS,SCH MED,PATHOL & ELECTRON MICROSCOPY,B-1070 BRUSSELS,BELGIUM

[2] UNIV BRUSSELS,SCH MED,HISTOL LAB,B-1070 BRUSSELS,BELGIUM

来源：

ARTHRITIS AND RHEUMATISM | 1990年 / 33卷 / 02期

关键词：

D O I：

10.1002/art.1780330217

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We describe a patient who developed acquired immunodeficiency syndrome‐related complex, complicated by chronic, symmetric polyarthritis. Synovial biopsy showed large areas of plasma cell infiltration subjacent to the synovial lining. Ultrastructural study demonstrated tubuloreticular structures within endothelial cells, crystal‐like inclusions in plasma cells, and virus‐like particles located around synoviocyte fragments. Although immunologic and morphologic studies did not permit classification of these virus‐like structures, the role of these possible virions in the pathogenesis of the observed synovitis remains to be determined. Surprisingly, the patient's chronic arthritis resolved with anti‐retroviral treatment (azidothymidine; AZT). Copyright © 1990 American College of Rheumatology

引用

页码：268 / 273

页数：6

共 19 条

[1] ISOLATION OF A NEW HUMAN RETROVIRUS FROM WEST-AFRICAN PATIENTS WITH AIDS [J].

CLAVEL, F ;

GUETARD, D ;

BRUNVEZINET, F ;

CHAMARET, S ;

REY, MA ;

SANTOSFERREIRA, MO ;

LAURENT, AG ;

DAUGUET, C ;

KATLAMA, C ;

ROUZIOUX, C ;

KLATZMANN, D ;

CHAMPALIMAUD, JL ;

MONTAGNIER, L .

SCIENCE, 1986, 233 (4761) :343-346

[2] CHRONIC ARTHRITIS IN GOATS CAUSED BY A RETROVIRUS [J].

CRAWFORD, TB ;

ADAMS, DS ;

CHEEVERS, WP .

SCIENCE, 1980, 207 (4434) :997-999

[3]

DAVIS P, 1988, LANCET, V1, P936

[4] PSORIATIC-ARTHRITIS AND ACQUIRED IMMUNODEFICIENCY SYNDROME [J].

ESPINOZA, LR ;

BERMAN, A ;

VASEY, FB ;

CAHALIN, C ;

NELSON, R ;

GERMAIN, BF .

ARTHRITIS AND RHEUMATISM, 1988, 31 (08) :1034-1040

[5] ULTRASTRUCTURAL DEMONSTRATION OF RETROVIRUS ANTIGENS WITH IMMUNO-GOLD STAINING IN PRODROMAL ACQUIRED IMMUNE-DEFICIENCY SYNDROME [J].

FEREMANS, WW ;

MENU, R ;

GOLDMAN, M ;

SCHANDENE, L ;

PORTETELLE, D ;

CLEUTER, Y ;

FLAMENT, J ;

DUSTIN, P ;

WYBRAN, J ;

BURNY, A .

JOURNAL OF CLINICAL PATHOLOGY, 1984, 37 (12) :1399-1403

[6] 50 CASES OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTION - IMMUNOULTRASTRUCTURAL STUDY OF CIRCULATING LYMPHOCYTES [J].

FEREMANS, WW ;

HUYGEN, K ;

MENU, R ;

FARBER, CM ;

DECALUWE, JP ;

VANVOOREN, JP ;

MARCELIS, L ;

ANDRE, L ;

BRASSEUR, M ;

BONDUE, H ;

LEBON, B ;

CLUMECK, N .

JOURNAL OF CLINICAL PATHOLOGY, 1988, 41 (01) :62-71

[7] THE EFFICACY OF AZIDOTHYMIDINE (AZT) IN THE TREATMENT OF PATIENTS WITH AIDS AND AIDS-RELATED COMPLEX - A DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL [J].

FISCHL, MA ;

RICHMAN, DD ;

GRIECO, MH ;

GOTTLIEB, MS ;

VOLBERDING, PA ;

LASKIN, OL ;

LEEDOM, JM ;

GROOPMAN, JE ;

MILDVAN, D ;

SCHOOLEY, RT ;

JACKSON, GG ;

DURACK, DT ;

KING, D .

NEW ENGLAND JOURNAL OF MEDICINE, 1987, 317 (04) :185-191

[8] INFLAMMATORY JOINT DISEASE AND HUMAN IMMUNODEFICIENCY VIRUS-INFECTION [J].

FORSTER, SM ;

SEIFERT, MH ;

KEAT, AC ;

ROWE, IF ;

THOMAS, BJ ;

TAYLORROBINSON, D ;

PINCHING, AJ ;

HARRIS, JRW .

BRITISH MEDICAL JOURNAL, 1988, 296 (6637) :1625-1627

[9] On multiple myelocytoma with peculiar crystalline cell structures, combined with elastolysis and extensive amyloidosis and calcification. [J].

Glaus, A .

VIRCHOWS ARCHIV FUR PATHOLOGISCHE ANATOMIE UND PHYSIOLOGIE UND FUR KLINISCHE MEDIZIN, 1917, 223 (03) :301-339

[10]

Haftek M., 1976, MED J AUSTRALIA, V7th ed.

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