INFLUENCE OF GLUCOSE-METABOLISM ON NYCTHEMERAL BLOOD-PRESSURE VARIABILITY IN HYPERTENSIVES WITH AN ELEVATED WAIST-HIP RATIO - A LINK WITH ARTERIAL DISTENSIBILITY

被引：25

作者：

AMAR, J ^{[1
]}

CHAMONTIN, B ^{[1
]}

PELISSIER, M ^{[1
]}

GARELLI, I ^{[1
]}

SALVADOR, M ^{[1
]}

机构：

[1] CHU PURPAN,SERV MED INTERNE & HYPERTENS ARTERIELLE,F-31059 TOULOUSE,FRANCE

来源：

AMERICAN JOURNAL OF HYPERTENSION | 1995年 / 8卷 / 04期

关键词：

NYCTHEMERAL BP VARIABILITY; AMBULATORY BP MONITORING; GLUCOSE INTOLERANCE; ARTERIAL DISTENSIBILITY;

D O I：

10.1016/0895-7061(94)00186-F

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

We studied the influence of glucose metabolism on the nycthemeral blood pressure (BP) pattern and arterial distensibility in 33 nontreated hypertensive patients, 45.6 +/- 8.5 years old, with elevated waist/hip ratio. All patients underwent an ambulatory BP monitoring, a pulse wave velocity (PWV) measurement, and an oral glucose tolerance test. The ratio of mean nocturnal:diurnal systolic BP (N/D ratio) was used to assess nycthemeral BP variability. N/D ratio correlated positively with PWV (r = 0.62; P < .01). When considered according to their glycemic status, N/D ratio and PWV were significantly higher (P < .05; P < .01) in diabetics and in glucose intolerants compared to patients with normal glucose levels. Our data indicate that the nycthemeral BP pattern was different according to the metabolic status. The loss of nocturnal decline in BP is associated with carbohydrate disturbances and reduced arterial stiffness.

引用

页码：426 / 428

页数：3

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