PROPRANOLOL PHARMACODYNAMIC MODELING USING UNBOUND AND TOTAL CONCENTRATIONS IN HEALTHY-VOLUNTEERS

被引：20

作者：

LALONDE, RL ^{[1
]}

STRAKA, RJ ^{[1
]}

PIEPER, JA ^{[1
]}

BOTTORFF, MB ^{[1
]}

MIRVIS, DM ^{[1
]}

机构：

[1] UNIV TENNESSEE,CTR HLTH SCI,DEPT MED,MEMPHIS,TN 38163

来源：

JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS | 1987年 / 15卷 / 06期

关键词：

D O I：

10.1007/BF01068413

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：569 / 582

页数：14

共 24 条

[1]

Akaike H., 1976, MATH SCI, V14, P5

[2] IMPORTANCE OF RADIOCHEMICAL PURITY OF RADIOLABELED DRUGS USED FOR DETERMINING PLASMA-PROTEIN BINDING OF DRUGS [J].

BJORNSSON, TD ;

BROWN, JE ;

TSCHANZ, C .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1981, 70 (12) :1372-1373

[3]

BRADDE OE, 1983, CIRC RES, V53, P752

[4]

CHIDSEY C, 1976, POSTGRAD MED J, V52, P26

[5] PLASMA PROPRANOLOL LEVELS IN QUANTITATIVE ASSESSMENT OF BETA-ADRENERGIC BLOCKADE IN MAN [J].

COLTART, DJ ;

SHAND, DG .

BRITISH MEDICAL JOURNAL, 1970, 3 (5725) :731-&

[6]

GOLDSTEIN A, 1974, PRINCIPLES DRUG ACTI, P82

[7]

HARMS H, 1976, J PHARM EXP THER, V19, P329

[8] KINETICS OF PHARMACOLOGIC RESPONSE [J].

HOLFORD, NHG ;

SHEINER, LB .

PHARMACOLOGY & THERAPEUTICS, 1982, 16 (02) :143-166

[9] ERRORS IN ESTIMATING THE UN-BOUND FRACTION OF DRUGS DUE TO THE VOLUME SHIFT IN EQUILIBRIUM DIALYSIS [J].

HUANG, J .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1983, 72 (11) :1368-1369

[10]

HUANG JD, 1982, J PHARMACOL EXP THER, V223, P469

← 1 2 3 →