THE RELATIONSHIP BETWEEN STRUCTURE AND ANTIMICROBIAL ACTIVITY IN QUINONES FROM THE CELASTRACEAE

被引:31
作者
MOUJIR, L [1 ]
GUTIERREZNAVARRO, AM [1 ]
GONZALEZ, AG [1 ]
RAVELO, AG [1 ]
LUIS, JG [1 ]
机构
[1] CTR PROD NAT ORGAN ANTONIO GONZALEZ,E-38206 TENERIFE,SPAIN
关键词
antimicrobial activity; bacteria; Celastraceae; Maytenus horrida; Schaefferia cuneifolia; triterpene quinones;
D O I
10.1016/0305-1978(90)90028-E
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Triterpene quinones and related compounds isolated from Schaefferia cuneifolia Standley and Maytenus horrida Reiss were assayed for antimicrobial activity on 18 different bacteria and one yeast. Compounds which had a triterpene quinone skeleton and groups in ring E tested positive, with maximum activity when there was a carboxyl group at C-20. These substances were more or less effective against Gram positive bacteria and the yeast, but did not affect Gram negative bacteria. © 1990.
引用
收藏
页码:25 / 28
页数:4
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