A DELETION TRUNCATING THE GONADOTROPIN-RELEASING-HORMONE GENE IS RESPONSIBLE FOR HYPOGONADISM IN THE HPG MOUSE

被引：514

作者：

MASON, AJ

HAYFLICK, JS

ZOELLER, RT

YOUNG, WS

PHILLIPS, HS

NIKOLICS, K

SEEBURG, PH

机构：

[1] NIMH,CELL BIOL LAB,BETHESDA,MD 20892

[2] UNIV CALIF SAN FRANCISCO,DEPT PHYSIOL,SAN FRANCISCO,CA 94143

来源：

SCIENCE | 1986年 / 234卷 / 4782期

关键词：

D O I：

10.1126/science.3024317

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：1366 / 1371

页数：6

共 34 条

[1] ISOLATION OF THE GENE AND HYPOTHALAMIC CDNA FOR THE COMMON PRECURSOR OF GONADOTROPIN-RELEASING-HORMONE AND PROLACTIN RELEASE-INHIBITING FACTOR IN HUMAN AND RAT [J].

ADELMAN, JP ;

MASON, AJ ;

HAYFLICK, JS ;

SEEBURG, PH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (01) :179-183

[2]

BENNETTCLARKE C, 1982, CELL TISSUE RES, V221, P493

[3] GONADOTROPHIN-RELEASING HORMONE DEFICIENCY IN A MUTANT MOUSE WITH HYPOGONADISM [J].

CATTANACH, BM ;

IDDON, CA ;

CHARLTON, HM ;

CHIAPPA, SA ;

FINK, G .

NATURE, 1977, 269 (5626) :338-340

[4] PROLACTIN MEASUREMENTS IN NORMAL AND HYPOGONADAL (HPG) MICE - DEVELOPMENTAL AND EXPERIMENTAL STUDIES [J].

CHARLTON, HM ;

SPEIGHT, A ;

HALPIN, DMG ;

BRAMWELL, A ;

SHEWARD, WJ ;

FINK, G .

ENDOCRINOLOGY, 1983, 113 (02) :545-548

[5]

CLARKE IJ, UNPUB

[6] PROMOTER SEQUENCES OF EUKARYOTIC PROTEIN-CODING GENES [J].

CORDEN, J ;

WASYLYK, B ;

BUCHWALDER, A ;

CORSI, PS ;

KEDINGER, C ;

CHAMBON, P .

SCIENCE, 1980, 209 (4463) :1406-1414

[7] FAMILIAL MONOTROPIC PITUITARY GONADOTROPIN INSUFFICIENCY [J].

EWER, RW .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1968, 28 (06) :783-+

[8] PRIMING EFFECT OF LUTEINIZING-HORMONE RELEASING HORMONE IN THE HYPOGONADAL MOUSE [J].

FINK, G ;

SHEWARD, WJ ;

CHARLTON, HM .

JOURNAL OF ENDOCRINOLOGY, 1982, 94 (02) :283-287

[9] ISOLATION OF HIGH-MOLECULAR-WEIGHT DNA FROM MAMMALIAN-CELLS [J].

GROSS-BELLARD, MM ;

OUDET, P ;

CHAMBON, P .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1973, 36 (01) :32-38

[10]

HAYFLICK JS, UNPUB

← 1 2 3 4 →