BASIC PHYSICS OF MR CONTRAST AGENTS AND MAXIMIZATION OF IMAGE-CONTRAST

被引:114
作者
HENDRICK, RE [1 ]
HAACKE, EM [1 ]
机构
[1] UNIV COLORADO,HLTH SCI CTR,DEPT RADIOL,DENVER,CO 80262
来源
JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING | 1993年 / 3卷 / 01期
关键词
CONTRAST ENHANCEMENT; CONTRAST MEDIA; GADOLINIUM; IRON;
D O I
10.1002/jmri.1880030126
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
This review summarizes the physical basis of magnetic resonance (MR) imaging contrast agents, including both T1 agents, such as gadolinium-DTPA (diethylenetriaminepentaacetic acid), and T2 or T2* agents, such as superparamagnetic iron oxides. The maximization of image contrast and lesion visibility with contrast agents is described, and the use of contrast agents in MR angiography and perfusion imaging is discussed.
引用
收藏
页码:137 / 148
页数:12
相关论文
共 22 条
[1]  
Brasch RC, Bennett HF, Mechanisms of contrast enhancement for MRI, Contrast media in MRI. International Workshop, Berlin, February 1–3, 1990, pp. 9-14, (1990)
[2]  
Watson AD, Rocklage SM, Carvlin MJ, Contrast agents, Magnetic resonance imaging, pp. 372-425, (1992)
[3]  
Wolf GL, Contrast media in MRI, Contrast media in MRI. International Workshop, Berlin, February 1–3, 1990, pp. 15-17, (1990)
[4]  
Solomon I, Relaxation processes in a system of two spins, Phys Rev, 99, pp. 559-568, (1955)
[5]  
Blocmbergen N, Purcell EM, Pound RV, Relaxation effects in nuclear magnetic resonance absorption, Physical Review, 73, pp. 679-710, (1948)
[6]  
Fullerton GD, Physiologic basis of magnetic relaxation, Magnetic resonance imaging, pp. 88-108, (1992)
[7]  
Bousquet J-C, Saini S, Stark DD, Et al., Gd‐DTPA: characterization of a new paramagnetic complex, Radiology, 166, pp. 693-698, (1988)
[8]  
Haustein J, Niendorf HP, Schubeus P, Et al., Dosage of Gd‐DTPA: new results, Contrast media in MRI. International Workshop, Berlin, February 1–3, 1990, pp. 41-49, (1990)
[9]  
Report no. 23: report of the Task Group on Reference Man, pp. 273-285, (1975)
[10]  
Yuh WTC, Engelken JD, Muhonen MG, Et al., Experience with high‐dose gadolinium MR imaging in the evaluation of brain metastases, AJNR, 13, pp. 335-345, (1992)