LYMPH-NODE AND DISTANT METASTASES IN PATIENTS WITH SINONASAL CARCINOMA

被引:7
作者
MIYAGUCHI, M [1 ]
SAKAI, S [1 ]
TAKASHIMA, H [1 ]
HOSOKAWA, H [1 ]
机构
[1] KAGAWA MED SCH,DEPT RADIOL,KAGAWA 76107,JAPAN
关键词
PARANASAL SINUS NEOPLASMS; CARCINOMA; SQUAMOUS CELL; NEOPLASM; METASTASIS;
D O I
10.1017/S0022215100129986
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
A retrospective analysis of 34 cases of sine-nasal squamous cell or undifferentiated carcinoma in patients admitted between 1984 and 1992 was undertaken. Multimodality therapy incorporated radiation, surgery and chemotherapy. The five-year survival rate was 53 per cent. The local control rate was 82 per cent. Patients died of local failure (six), distant metastases (six), lymph node metastases (one) and other causes (three). Twenty-eight patients with local control were separated into groups: G1-2 (well and moderately differentiated) and G3-4 (poorly differentiated and undifferentiated) and evaluated to find the association between differentiation and metastasis. Lymph node metastasis was not related to the degree of differentiation. Distant metastasis was significantly related to the degree of differentiation (Fisher's exact test: p = 0.007). The result of the combination therapy is poor for patients with poorly differentiated or undifferentiated carcinoma because of distant metastases. Adjuvant chemotherapy may be necessary for them to prevent distant metastasis.
引用
收藏
页码:304 / 307
页数:4
相关论文
共 12 条
[1]  
GIRI SPG, 1992, CANCER, V69, P657, DOI 10.1002/1097-0142(19920201)69:3<657::AID-CNCR2820690310>3.0.CO
[2]  
2-7
[3]  
KNEGT PP, 1985, CANCER, V56, P57, DOI 10.1002/1097-0142(19850701)56:1<57::AID-CNCR2820560110>3.0.CO
[4]  
2-#
[5]  
KONDO M, 1984, CANCER, V53, P2206, DOI 10.1002/1097-0142(19840515)53:10<2206::AID-CNCR2820531034>3.0.CO
[6]  
2-J
[7]   SURVIVAL AFTER SURGICAL-TREATMENT IN MAXILLARY NEOPLASMS OF EPITHELIAL ORIGIN [J].
LINDEMAN, P ;
EKLUND, U ;
PETRUSON, B .
JOURNAL OF LARYNGOLOGY AND OTOLOGY, 1987, 101 (06) :564-568
[8]  
SAKAI S, 1983, CANCER, V52, P1360, DOI 10.1002/1097-0142(19831015)52:8<1360::AID-CNCR2820520804>3.0.CO
[9]  
2-#
[10]  
Sakai S, 1983, Rhinology, V21, P179