ODORANTS OF THE SAME ODOR CLASS ACTIVATE DIFFERENT 2ND MESSENGER PATHWAYS

被引:130
作者
BREER, H
BOEKHOFF, I
机构
[1] University Stuttgart-Hohenheim, Department of Zoophysiology, 7000 Stuttgart 70
关键词
D O I
10.1093/chemse/16.1.19
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
A number of chemicals with the same odor quality (fruity, floral, herbaceous, putrid) were assayed for their potential to activate second messenger pathways in cilia preparations from rat olfactory epithelia using a rapid-quench flow procedure. It was found that compounds with similar odor do not all activate the same second messenger but rather induced the formation of either cyclic adenosine monophosphate or inositol triphosphate. Thus, alternative reaction cascades can be activated by chemicals with a similar odor quality.
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页码:19 / 29
页数:11
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