REGULATION OF PROGRESSION THROUGH THE G1 PHASE OF THE CELL-CYCLE BY THE RUM1(+) GENE

被引:311
作者
MORENO, S
NURSE, P
机构
[1] ICRF, LONDON WCZA 3PX, ENGLAND
[2] UNIV OXFORD, DEPT BIOCHEM, ICRF, CELL CYCLE GRP, OXFORD OX1 1QU, ENGLAND
关键词
D O I
10.1038/367236a0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The rum1+ gene is identified as a new regulator of G1 progression in fission yeast. It influences three aspects of G1 regulation: determination of the length of G1, dependence of S phase upon completion of mitosis, and restraint of mitosis until G1 is finished. We propose that it has a central role in regulating the G1 phase of the cell cycle.
引用
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页码:236 / 242
页数:7
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