QUANTITATIVE OVER-PRESSURE LAYER CHROMATOGRAPHY OF QUININE, QUINIDINE, AND HYDROQUINIDINE IN BIOMEDICAL ANALYSIS

被引：2

作者：

DETOLLE, S ^{[1
]}

POSTAIRE, E ^{[1
]}

PROGNON, P ^{[1
]}

MONTAGNIER, C ^{[1
]}

PRADEAU, D ^{[1
]}

机构：

[1] HOP BEAUJON,F-92120 CLICHY,FRANCE

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY | 1990年 / 13卷 / 10期

关键词：

D O I：

10.1080/01483919008049007

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

An over-pressure layer chromatography (OPLC) method for the separation and quantification of quinine, quinidine and hydroquinidine is discussed in this paper. After the development with the mobile phase methanol-acetonitrile-ammonia 0, 2M (130:68 :2, v/v), a densitometric detection was performed by the fluorescence emission (excitation wavelength = 348 nm; emission wavelengh = 420 nm). This technique is simple, fast and adapted to small series of determination for the quality control and therapeutic drug monitoring. © 1990, Taylor & Francis Group, LLC. All rights reserved.

引用

页码：1991 / 2000

页数：10

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