NEW METHODOLOGY FOR CONJUGATE ADDITIONS OF ALLYLIC LIGANDS TO ALPHA,BETA-UNSATURATED KETONES - SYNTHETIC AND SPECTROSCOPIC STUDIES

Michael additions of allylic ligands, including allyl, methallyl, crotyl, and prenyl systems, to a variety of α, β -unsaturated ketones can be effected in synthetically useful yields with allylcopper reagents in the presence of trimethylchlorosilane. Low-temperature13C NMR spectral studies suggest that the allylic ligands are σ-bound to copper. © 1990, American Chemical Society. All rights reserved.