DOSE-RESPONSE CURVE SLOPE IMPROVEMENT AND RESULT REPRODUCIBILITY OF FERROUS-SULFATE-DOPED GELS ANALYZED BY NMR IMAGING

被引：48

作者：

GAMBARINI, G ^{[1
]}

ARRIGONI, S ^{[1
]}

CANTONE, MC ^{[1
]}

MOLHO, N ^{[1
]}

FACCHIELLI, L ^{[1
]}

SICHIROLLO, AE ^{[1
]}

机构：

[1] IST NAZL STUDIO & CURA TUMORI,I-20133 MILAN,ITALY

来源：

PHYSICS IN MEDICINE AND BIOLOGY | 1994年 / 39卷 / 04期

关键词：

D O I：

10.1088/0031-9155/39/4/004

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Ferrous sulphate gel analysed by relaxation time measurements with NMR imaging is considered a useful dosimeter for 3D determinations of absorbed dose. A protocol for the gel preparation with agarose SeaPlaque that leads to a dosimeter with very high dose sensitivity is described. The dose-response curve slope is about 0.2 s(-1) Gy(-1) and the G factor turns out to be similar to 185 ions per 100 eV of absorbed energy. A method for making the measurements and analysing the results that brings about good result reproducibility is suggested. A thorough experimental study of the dependence of the dosimeter response on the elapsed time from preparation to irradiation and from irradiation to NMR measurement has revealed good reproducibility. The above characteristic of the gel system is very interesting, because it shows the possibility of utilizing the dosimeter for absolute dose determinations with satisfactory reliability.

引用

页码：703 / 717

页数：15

共 11 条

[1] IMAGING OF SPATIAL RADIATION-DOSE DISTRIBUTION IN AGAROSE GELS USING MAGNETIC-RESONANCE [J].