STRUCTURES OF DICHLORO[(S)-METHIONINE-N,S]PLATINUM(II) AND CHLORO[GLYCYL-(S)-METHIONINATO-N,N',S]PLATINUM(II) MONOHYDRATE

(I) [Pt{CH3SCH2CH2CH(NH2)COOH-}Cl2], M(r) = 415.20, monoclinic, P2(1), a = 7.578 (2), b = 10.213 (2), c = 13.563 (4) angstrom, beta = 98.77 (1)-degrees, V = 1037.4 (4) angstrom 3, D(x) = 2.657 g cm-3 for Z = 4, lambda(Mo K-alpha) = 0.71069 angstrom, mu = 142.81 cm-1, F(000) = 768, T = 294 K, final R = 0.029 for 2980 reflections. (II) [Pt{H2NCH2CONCH(CO2H)CH2CH2SCH3}-Cl].H2O, M(r) = 453.81, orthorhombic, P2(1)2(1)2(1), a = 6.9971 (4), b = 10.6246 (9), c = 16.965 (1) angstrom, V = 1261.2 (2) angstrom 3, D(x) = 2.389 g cm-3 for Z = 4, lambda(Mo K-alpha) = 0.71069 angstrom, mu = 115.69 cm-1, F(000) = 856, T = 294 K, final R = 0.021 for 1820 reflections. The structures of the title complexes have been redetermined using high-resolution data. In the asymmetric unit of (I) there are two independent diastereomeric molecules, the S atoms having opposite chiralities. The amino acid coordinates via the N(amino) and S(thioether) atoms, Pt-N(amino) 2.047 (8), 2.029 (8), Pt-S 2.246 (2), 2.247 (2) angstrom. In (II) the dipeptide coordinates via the N(amino), N(peptide) and S(thioether) atoms, Pt-N(amino) 2.046 (5), Pt-N(peptide) 2.004 (4), Pt-S 2.258 (2) angstrom.