CRYSTALLIZATION AND PRELIMINARY DIFFRACTION ANALYSIS OF CAUDOXIN AND NOTEXIN - 2 MONOMERIC PHOSPHOLIPASE-A2 NEUROTOXINS

被引：2

作者：

SCOTT, DL

ACHARI, A

CHRISTENSEN, PA

VILJOEN, CC

SIGLER, PB

机构：

[1] YALE UNIV,DEPT MOLEC BIOPHYS & BIOCHEM,JWG 404,260 WHITNEY AVE,NEW HAVEN,CT 06511

[2] DEPT NATL HLTH POPULAT DEV,FORENS CHEM LAB,PRETORIA 0001,SOUTH AFRICA

[3] YALE UNIV,HOWARD HUGHES MED INST,NEW HAVEN,CT 06511

[4] UNIV CHICAGO,DEPT BIOCHEM & MOLEC BIOL,CHICAGO,IL 60637

来源：

TOXICON | 1991年 / 29卷 / 12期

关键词：

D O I：

10.1016/0041-0101(91)90009-G

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Two monomeric neurotoxic phospholipases A2 have been crystallized and their diffraction properties characterized. Crystals of caudoxin (from the venom of Bitis caudalis) and notexin (from the venom of Notechis scutatus scutatus) were grown at neutral pH, in the absence of calcium ion, and diffract to a resolution of 2.3 and 1.6 angstrom, respectively.

引用

页码：1517 / 1521

页数：5

共 18 条

[1]

ACHARI A, 1985, J BIOL CHEM, V260, P9385

[2]

BRUNIE S, 1985, J BIOL CHEM, V260, P9742

[3] STRUCTURE OF BOVINE PANCREATIC PHOSPHOLIPASE-A2 AT 1.7A RESOLUTION [J].