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A FATALITY INVOLVING 2 UNUSUAL COMPOUNDS ZOLPIDEM AND ACEPROMAZINE
被引：26
作者：
TRACQUI, A
KINTZ, P
MANGIN, P
机构：
[1] Institut de Medecine Legale, 67085 Strasbourg Cedex
关键词：
ACEPROMAZINE;
DIODE ARRAY;
TOXICOLOGY;
HIGH-PRESSURE LIQUID CHROMATOGRAPHY;
POISONING;
ZOLPIDEM;
D O I：
10.1097/00000433-199312000-00007
中图分类号：
DF [法律];
D9 [法律];
R [医药、卫生];
学科分类号：
0301 ;
10 ;
摘要：
A fatality due to ingestion of zolpidem, a recently developed nonbenzodiazepine hypnotic, and acepromazine, a phenothiazine sedative used in veterinary practice, is reported. Both drugs were identified and quantified using high-performance liquid chromatography with diode-array detection. Zolpidem and acepromazine blood concentrations were 3.29 and 2.40 mug/ml, respectively. It is the first report of a death involving either of these two drugs. The results are discussed in the light of the existing literature and may suggest a reciprocal potentiation of the toxic effects of zolpidem and phenothiazines.
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页码：309 / 312
页数：4
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