RED-CELL MEMBRANE-PROTEIN LATERAL MOBILITY IN DIABETES-MELLITUS

被引：7

作者：

CAIMI, G ^{[1
]}

SERRA, A ^{[1
]}

LOPRESTI, R ^{[1
]}

SARNO, A ^{[1
]}

机构：

[1] UNIV PALERMO, IST CLIN MED & MALATTIE CARDIOVASC, I-90134 PALERMO, ITALY

来源：

HORMONE AND METABOLIC RESEARCH | 1992年 / 24卷 / 09期

关键词：

RED CELL MEMBRANE PROTEINS; DIABETES-MELLITUS;

D O I：

10.1055/s-2007-1003347

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In a group of 24 diabetics subdivided for type, we evaluated the red cell membrane protein lateral mobility marking intact red cells with pyrene-3-maleimide (3-PM) and calculating the dimer to monomer fluorescence intensity ratio (Iex/Im). The same fluorescent parameter was determined in a group of 13 normal controls. From the obtained data, it is evident that the red cell membrane protein lateral mobility clearly discriminates normals from diabetics of type 1 and 2. In normals and in diabetics of type 1 and 2 no relationship is present between this fluorescent determinant and the glycometabolic parameters (FBGL and HbA1c); considering all the diabetics, a negative relationship is evident between Iex/Im ratio and HbA1c only.

引用

页码：409 / 411

页数：3

共 24 条

[1] DYNAMICS OF ERYTHROCYTE LIPIDS IN INTACT-CELLS, IN GHOST MEMBRANES AND IN LIPOSOMES [J].