CISPLATIN-RESISTANT METASTATIC HEPATOBLASTOMA - COMPLETE RESPONSE TO CARBOPLATIN, ETOPOSIDE, AND LIVER-TRANSPLANTATION

被引：24

作者：

LOCKWOOD, L

HENEY, D

GILES, GR

LEWIS, IJ

BAILEY, CC

机构：

[1] ST JAMES UNIV HOSP,DEPT PAEDIAT ONCOL,LEEDS LS9 7TF,W YORKSHIRE,ENGLAND

[2] ST JAMES UNIV HOSP,DEPT SURG,LEEDS LS9 7TF,W YORKSHIRE,ENGLAND

来源：

MEDICAL AND PEDIATRIC ONCOLOGY | 1993年 / 21卷 / 07期

关键词：

HEPATOBLASTOMA; CARBOPLATIN; LIVER TRANSPLANT;

D O I：

10.1002/mpo.2950210711

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A child with stage 4 hepatoblastoma failed to respond to treatment with cisplatin and adriamycin. She then showed a response to carboplatin with complete clearing of pulmonary metastases. Bilobar liver disease persisted, although significantly reduced in size. A liver transplant was subsequently performed and she remains in complete remission 36 months later. After the first course of carboplatin, there was a dramatic rise in alpha-feto protein which then fell exponentially. Carboplatin warrants further study in hepatoblastoma. (C) 1993 Wiley-Liss, Inc.

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收藏

页码：517 / 520

页数：4

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