A LARGE NUMBER OF TRANSFER-RNA GENES ARE SYMMETRICALLY LOCATED IN FISSION YEAST CENTROMERES

被引：44

作者：

TAKAHASHI, K

MURAKAMI, S

CHIKASHIGE, Y

NIWA, O

YANAGIDA, M

机构：

[1] Department of Biophysics Faculty of Science, Kyoto University, Sakyo-ku, Kyoto

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1991年 / 218卷 / 01期

关键词：

D O I：

10.1016/0022-2836(91)90867-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We report here that the fission yeast centromere regions in the three chromosomes contain no less than 36 symmetrically arranged tRNA-coding sequences, and many of them are located within the inner inverted regions that are thought to be essential for the centromere function. There are 11 different species of tRNA-coding sequences, and four of them are identical to those previously known in this organism. This high-density distribution of tRNA genes in the centromere regions is surprising, as the fission yeast centromeres were thought to form transcriptionally inactive structures. © 1991.

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页码：13 / 17

页数：5

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